• The development, implementation, testing, and continued maintenance of the SRA data delivery and distribution pipelines; • Working with a diverse group of scientists, bioinformaticians and other developers across the SRA Program and NCBI to implement efficient bioinformatics algorithms and to further advance the usefulness of SRA data; • Design and implementation of sustainable and scalable services to be used by collaborators and scientists in the field. • Keeping abreast with new high throughput, distributed processing, and cloud technologies; • Keeping up with the internal systems designs and documentation, and sharing knowledge with the team; and • Ensuring compliance with NCBI, NLM, NIH and government standards and directives for software development and delivery, including privacy and security controls.

• 3+ years of experience developing highly available, high-traffic, distributed software applications; • Experience developing data and document submission interfaces and processing pipelines for bioinformatics data; • Knowledge of Next Generation Sequencing technologies, bioinformatics data formats and tools; • Ability to troubleshoot bugs and outages in production applications; • Experience introducing and managing Agile software development practices; • Proficiency in C++ and Python programming languages; • Fluency in scripting languages such as bash and csh; • Knowledge of AWS and GCP cloud technologies and modern web client frameworks; and • Experience implementing DevOps practices and Git workflow.

The IEB is responsible for designing and building NCBI's production software and databases. They: (1) perform applied research in the area of data representation and analysis for molecular biology data, including development of computer based systems for the storage, management, and retrieval of knowledge concerning molecular biology, genetics, and biochemistry; (2) design schema and specifications for representation of sequence genetic and structural information in databases which will serve as national resources; (3) design and develop distributed software systems from the prototype to operational phases which provide researchers with both local and remote computational services; (4) coordinate access to sequence, genetic, structural, and bibliographic databases; (5) establish collaborative informatics research projects with NIH Intramural laboratories as well as extramural academic groups; (6) consult and advise other government agencies and research laboratories on advanced methods of software and database design; and (7) develop and promote standards for databases, data exchange, and biological nomenclature. NCBI performs research in computational biology and creates and maintains information systems and computational tools for the biological research and clinical communities. This involves the organization and enhancement of NCBI’s sequence content and delivery of data, tools, and displays to accelerate research and maximize impact on human health. NCBI programs and activities supported by this position are highly complex, mission-critical, and have national and international impact, as they directly support the mission of NCBI - a greater than $150 million research organization with more than 700 staff. This position will contribute to development and maintenance of solutions to support continued development of NCBI’s Sequence Read Archive (SRA) – the world premier archive of Next Generation Sequencing (NGS) data and is a part of international collaboration that includes archives in Europe and Japan. SRA makes biological sequence data derived from NGS available to the research community to enhance reproducibility and allow for new discoveries by analyzing and comparing data sets. SRA is a BigData archive measured in tens of petabytes of stored data. The future development of SRA will make this data more useful for wide variety fields: Medical Health (e.g., genetic diseases, cancer, etc.), Public Health (e.g., food safety monitoring, antimicrobial resistance, viral outbreaks, etc.), microbial diversity, and many more.

Interested individuals should send a copy of their CV and Bibliography with the names of three references along with a cover letter detailing research interests, a brief summary of communication and organizational skills, and evidence of engagement in multi- disciplinary collaborative research to ncbijobs@ncbi.nlm.nih.gov. Please include the announcement number, NLM9802-2024, in the cover letter. Do not include your birth date, social security number (SSN), or personal photograph on application materials.

Selectees who have completed part or all their education outside of the United States must have their foreign education evaluated by an accredited organization to ensure that the foreign education is equivalent to education received in accredited educational institutions in the United States. We will only accept the completed foreign education evaluation. For more information on foreign education verification, visit the National Association of Credential Evaluation Services (NACES) website. Verification must be received prior to the effective date of the appointment.

Benefits:

Salary is commensurate with research experience and accomplishments. A full package of benefits, including retirement, health, life, and long-term care insurance, Thrift Savings Plan participation, etc., is available.

The successful candidate will serve in a non- competitive and time-limited, renewable appointment in the excepted service.