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Job Title: FDA Evaluation of Drug Toxicity on Placenta Immunity
Job Number:
Organization: US Food and Drug Administration (FDA)
Posted: 1/10/2022
Type: Full-Time
Number of Openings: 1
Location: Silver Spring,  MD    USA
Position Description: *Applications will be reviewed on a rolling- basis, and this posting will remain open until filled.

A research opportunity is currently available in the Office of Tissues and Advanced Therapies (OTAT) at the Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA) in Silver Spring, Maryland.

Many pregnant women take prescription drugs to treat health problems, such as chronic pain, diabetes, and high blood pressure. In addition to their direct adverse effects on the fetus, these drugs may be toxic to the placenta barrier and impair its ability to provide protective immunity to the fetus. This ability is attributed to the placenta’s resistance to microbial and viral infections and ability to transfer protective maternal antibodies to the fetus. It is critical to understand how prescription drugs adversely affect the placenta’s ability to provide immune protection to the fetus. The participant will receive training on how to develop a reliable, high-throughput screening platform to evaluate drug transport from maternal blood across the placenta barrier to fetal blood. Using the platform, the participant will also receive training on how experimental models can be used to understand the effect of a drug on placenta immunity, which may contribute to determining safe drugs that pregnant women could take. Training in this area will provide the participant with a better understanding of how the newly developed assays could be employed in the assessment of various products regulated at the FDA.

Anticipated Appointment Start Date: February 2022; start date is flexible

This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits.

Qualifications: The qualified candidate should be currently pursuing or have received a doctoral degree in one of the relevant fields. Degree must have been received within the past five years.

Organization Description:

Closing Date: 4/10/2022
Desired Starting Date:
Contact Name: N/A N/A,  FDA Evaluation of Drug Toxicity on Placenta Immunity
Contact Location:

Contact Location:
Contact Phone:  
Contact Fax:
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Web Address:
How to Apply: Applications must be completed in Zintellect at the Web Address provided.

Additional Information:

Web Site Delete Date: 4/10/2022