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Job Title: Bioinformatics Scientist (Cancer Genomics)
Job Number:
Organization: National Cancer Institute
Posted: 5/6/2024
Type: Full-Time
Classification: Informatics
Industry: Government
Number of Openings: 1
Location: Rockville,  MD    USA
Position Description: We are seeking a Bioinformatics Scientist to join the Integrative Tumor Epidemiology Branch (ITEB) of the Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute (NCI). The ITEB mission is to conduct large-scale, international epidemiological research on cancer etiology and progression through integrative analyses of risk factors and tissue profiling to inform prevention and clinical strategies. For further details about our program of research please see rams-hgp/iteb. The Bioinformatics Scientist will work closely with Earl Stadtman Principal Investigators Dr. Diptavo Dutta and Dr. Mitchell Machiela, and also in collaboration with senior bioinformaticians, epidemiologists, and trainees within ITEB and across other branches in DCEG. They will be responsible for accessing and analyzing large genetic and genomic databases from current and past studies. This includes but is not limited to data manipulation, algorithmic implementation, statistical programming, genetic/genomic analyses and presenting results to scientific community within and beyond DCEG. The position will provide support and expertise in installing, troubleshooting, and running analytical pipelines using open-source scientific software on Unix/Linux and Cloud- based platforms, and using publicly available bioinformatics and genomic databases and analysis pipelines. Data types can include genome-wide genotyping arrays, DNA sequencing, gene expressions, proteomic profiling, and methylation profiling, across a range of tissues and cancer types.

Qualifications: Required qualifications: 1. Master’s degree in bioinformatics, computational biology, data science, or a related field 2. Extensive programming experience in at least two of R, Python and C++. 3. Familiarity with Unix/Linux system, bash or similar scripts and high performance computing clusters 4. Team oriented with excellent written and verbal communication skills, with demonstrated ability to learn and adopt bioinformatics techniques and resources.

Preferred qualifications: 1. Experience in processing and analyzing large genetic and genomic files (VCFs, PLINK binary) 2. Experience in standard genetic association analysis software like PLINK, GCTA etc. 3. Familiarity and working knowledge of tools to query and investigate cancer genomics with publicly available data sources (such as dbGaP, TCGA, ENCODE, 1000 Genomes, GTEX, gnomAD, cBioPortal, TCPA) 4. Experience in performing statistical analysis of large datasets by running open source and custom developed analysis pipelines in R/Python/C++.

Organization Description: The NCI is an exciting place to work, and the position provides excellent learning opportunities and possibilities for professional advancement. Pay is commensurate with qualifications and includes a comprehensive benefit package. This is a contract position at a government agency in Rockville, Maryland. Please send resume and cover letter addressing your qualifications for the position to with an email title of “Bioinformatics Scientist Application”. The position will remain open until it is filled.

Closing Date: 8/6/2024
Desired Starting Date:
Contact Name: Sylvia Roberts,  Bioinformatics Scientist (Cancer Genomics)
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